Outlook error 0x80040201 can be caused by various factors, including incorrect SMTP settings, third-party antivirus, add-ons and more. Many users have reported that they see such an error code when they try to send an email to a recipient.. In some cases, according to some user reports, they can send an email while replying to one received. However, when they try to write an email from scratch and then send it, an error code appears with the following message code.

Many users use the Outlook desktop application on their Windows operating system 10. However, like any other app, you run into a problem from time to time. You can correct the error by implementing the solutions given below.
What Causes Outlook Error 0x80040201?
Well, the error can arise for various reasons, since there is no specific cause that we can blame for everything. Then, to list possible reasons, the error is often due to the following factors:
- Incorrect SMTP configuration: There are certain scenarios where your account is switched from Exchange to POP3 email. In such cases, removing the autocomplete list seems to fix the problem.
- Third-party antivirus: In some cases, the third-party antivirus on your system may also be the culprit. The antivirus may be blocking the request to send the email that is causing the problem.
- Third party plugins: Many users use third-party add-ins in Outlook. These plugins can occasionally cause certain problems, in which case you will have to delete them.
Now that you have a basic understanding of the possible causes of the error, You can implement the following solutions to avoid the problem.
Solution 1: disable third-party antivirus
The first step to isolate the problem would be to disable the third-party antivirus that is running on your system.. Antiviruses often impose restrictions and block various requests sent by the system due to which various errors occur. Therefore, before trying the other solutions, make sure to disable third party antivirus, if you are using one.

Solution 2: Run Outlook in safe mode
Regarding the second solution, as we have already mentioned, another possible factor in the problem would be third-party add-ins in Outlook. These plugins are usually responsible for causing certain problems with the application, so in such cases it is necessary to remove them.
First, you will have to run Outlook in safe mode to see if it isolates the problem. Running in safe mode will not include third-party plugins, so you can see if the plugins are really the cause of the error. In case you can send an email without problems in Safe Mode, that means third party plugins are actually the cause of the problem. In that case, you will have to delete them. Then, explains how to run Outlook in safe mode:
-
Press the Windows key + R to open the Run dialog.
-
Type the following and then hit Enter:
Outlook /safe
Run Outlook in safe mode
-
This will open Microsoft Outlook in safe mode.
If you can send an email successfully, you can remove the plugins by doing the following:
-
Abra Outlook.
-
Go to File and then navigate to Options.
-
Switch to Plugins tab and remove any third party plugins you have added.
Outlook Add-ons
-
Restart the app.
Solution 3: empty autocomplete list
As mentioned earlier, in some scenarios, if you have created an Exchange account, your email becomes POP3 due to Outlook application searching for AutoComplete contacts that were in Exchange AutoComplete list. Once the list is empty, the Outlook application will start searching the .PST file for AutoComplete contacts. This will also rebuild the AutoComplete list steadily. Here's how to clear the list:
-
Abra Microsoft Outlook.
-
Go to File and then navigate to Options.
-
Switch to the Mail tab and scroll down until you find $ 0027 Send messages $ 0027.
-
Click the button $ 0027 Empty autocomplete list $ 0027.
Empty autocomplete list
-
Then click OK.
Hopefully, this will fix your problem.
Related Post:
- ▷ What is the application for registration of a digital TV tuner device and should be removed?
- ⭐ Top 10 IPTV players for Windows [2020]
- ⭐ How to get free Fortnite accounts with Skins?
- ▷ How do I fix the error code “WS-37403-7” and PlayStation 4?
- ▷ The 5 best browsers for Windows XP
- ▷ How to disable Adobe AcroTray.exe from startup
Run Outlook in safe mode
Outlook Add-ons
Empty autocomplete list



